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Amiodarone was perfectly tolerated and did not boost the chance of intraoperative or postoperative complications. Amiodarone therapy was not linked to proarrhythmia or critical adverse reactions, even among the sufferers with extreme coronary and valvular heart problems. Among the many individuals who did have atrial fibrillation, amiodarone decreased the ventricular rate more noticeably than did placebo.

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Even though the assigned health care therapy was discontinued about the day of discharge, the incidence of atrial fibrillation was appreciably lessen while in the amiodarone group than during the placebo group in the course of the period of time quickly next discharge.

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Facts on hospitalization prices for the study population had been provided in the use of a commercially out there final decision-aid facts software package procedure (Model 204, Transition Methods, Boston), operated with the College of Michigan Spending plan Office. These data depict the sum of variable direct charges, mounted direct expenses, and indirect charges.

Atrial fibrillation occurs frequently immediately after open up-coronary heart operation and will hold off clinic discharge. The goal of this research was to assess using preoperative amiodarone as prophylaxis against atrial fibrillation soon after cardiac surgery.

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